Lots of people in this thread more qualified than I to answer that question. Since you asked and I'm bored at the moment..............
1.) 50:1 in a strato saw would in theory be the same amount of oil as ~75:1 in a non-strato saw. I'd never run that little oil. Academic for me, I don't own any strato saws, and still run richer than 50:1.
2.) The "right" amount of oil seems to vary hugely depending on usage. I'm a part time firewood cutter homeowner, most saws would last my entire life using 50:1 and be fine. Professional logger putting more trigger time in one day than I'll put in all year might burn up a saw in a hurry running that little oil.
3.) I'm a big fan of oil, I'll never understand the people that try to see how close they can get to running their equipment without oil. Even the best oil in the world doesn't do anything if it's not there. Oil is cheap and engines are expensive.
4.) Nothing to do with saws, but like I said, I'm a big fan of oil. I change the oil in my vehicles frequently too. Oil is cheap and engines are expensive.
5.) I'd bet a cup of coffee that more saws are killed by poor tuning than wrong oil mix. I'd rather run 50:1 with boat oil and the right tune than 16:1 with Red Armor and a lean tune.