The 165 a frame out of a 300 win mag is pretty decisive and if they run you typically will have a blood trail, which IME with a Barnes you will not.I used my 338RUM on a couple elk and a couple deer. 250gr swift Aframe are nicknamed "special non-tracking bullets" in deer camp. So far, one has yet to move post shot lol
Barnes have their place. IE using something like a 243 or 25-06 elk as they will shoot through both sides.