Barnes as a rule are pretty easy to get to shoot. At least the TSX and latter versions.Barnes or other all copper bullets...copper = less dense than lead.
So for example 150gr all copper bullet = longer than typical lead with copper jacket bullet.
The extra length completely changes everything. From powder charge, seating depth, to how the barrel twist acts on the bullet...accuracy.
Copper petals on the barnes seem to sheer off if velocity is to high...they seem to perform better with less velocity. The performance of the petals is the key factor for barnes as the base of the bullet will basically not deform vs your typical lead base can deform/expand out somewhat depending on velocity and what it hits.
IME you really need all the velocity you can get with them and be sure you hit bone. If not all bets are off and even if the above conditions are met they still are inconsistent.