I also try to use ball power when I can. One thing, when working with 6mm Rem and 22-250 I found necking closer to the lands would make the bullet strike higher. Every caliber and chambering has a sweet spot for bullet weight, speed, and bullet drop like 22-250 is 55g bullet weight, 222/223 50g, 6mm Rem and 243 win is 85g. 25-06 100g.
The ballistic advantage of matching bullet weight and speed in a caliber for flat trajectory is where I normally start. I look for a bullet weight and performance that best fits the game I am hunting. My favorites have always been nosler solid base, you could shoot a lighter bullet for better trajectory and get the same performance that you get with a heavier weight bullet.